The Anti-TET3 Antibody (CAB20501) is a specialized tool for research involving Tet methylcytosine dioxygenase 3 (TET3), an enzyme involved in DNA demethylation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been rigorously validated for use in Western blot applications. By binding specifically to the TET3 protein, researchers can accurately detect and study its expression levels in various cell types, making it an essential tool for studies in epigenetics, gene regulation, and developmental biology.TET3 is a key player in DNA demethylation processes, regulating gene expression and cellular differentiation.
Its involvement in maintaining the epigenetic landscape makes it a target of interest in cancer research, developmental biology, and stem cell biology. Unraveling the mechanisms by which TET3 functions is crucial for understanding its role in disease progression and potentially identifying novel therapeutic targets.Overall, the Anti-TET3 Antibody (CAB20501) serves as a valuable tool for investigating the functions and regulatory processes of TET3 in various biological contexts, offering insights into epigenetic mechanisms and potential avenues for therapeutic intervention.
Product Name:
TET3 Rabbit Polyclonal Antibody
SKU:
CAB20501
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of mouse TET3 (Q8BG87).
cytoplasm, female pronucleus, male pronucleus, nucleoplasm, nucleus
Calculated MW:
195kDa
Observed MW:
230kDa
Enables methylcytosine dioxygenase activity. Involved in DNA demethylation of male pronucleus. Acts upstream of or within DNA demethylation. Located in cytoplasm; female pronucleus; and male pronucleus. Is expressed in several structures, including central nervous system; early conceptus; future brain; and genitourinary system. Orthologous to human TET3 (tet methylcytosine dioxygenase 3).
Purification Method:
Affinity purification
Gene ID:
194388
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with TET3 using TET3 Rabbit pAb(CAB20501) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
