TET2 Rabbit Polyclonal Antibody (CAB20365)
- SKU:
- CAB20365
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- Ayu17-44
- Ayu17-449
- mKIAA1546
- E130014J05Rik
Description
Product Name: | TET2 Rabbit Polyclonal Antibody |
SKU: | CAB20365 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 288-448 of mouse TET2 (NP_001035490.2). |
Sequence: | NASK PAIV PGTC PFQK AEHQ QKSA LDIG PSRA ENKT IQGS MELF AEEY YPSS DRNL QASH GSSE QYSK QKET NGAY FRQS SKFP KDSI SPTT VTPP SQSL LAPR LVLQ PPLE GKGA LNDV ALEE HHDY PNRS NRTL LREG KIDH QPKT SSSQ SLNP SVHT P |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | Ayu17-449; mKIAA1546; E130014J05Rik; TET2 |
Positive Sample: | F9,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | nucleoplasm, nucleus |
Calculated MW: | 212kDa |
Observed MW: | 280kDa |
Enables methylcytosine dioxygenase activity. Involved in cellular protein modification process; myeloid cell differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including DNA demethylation; animal organ development; and hematopoietic stem cell homeostasis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; extraembryonic component; lower urogenital tract; reproductive system; and urethra epithelium. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); lung non-small cell carcinoma; and primary immunodeficiency disease. Orthologous to human TET2 (tet methylcytosine dioxygenase 2).
Purification Method: | Affinity purification |
Gene ID: | 214133 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |