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TCP1 alpha Rabbit Monoclonal Antibody (CAB3887)

SKU:
CAB3887
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CCT-alpha
CCT1
CCTa
D6S230E
TCP-1-alpha
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TCP1 alpha Rabbit Monoclonal Antibody
SKU:CAB3887
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TCP1 alpha (P17987).
Sequence:MEGP LSVF GDRS TGET IRSQ NVMA AASI ANIV KSSL GPVG LDKM LVDD IGDV TITN DGAT ILKL LEVE HPAA KVLC ELAD LQDK EVGD GTTS VVII AAEL
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:CCT1; CCTa; D6S230E; CCT-alpha; TCP-1-alpha; TCP1 alpha
Positive Sample:Jurkat
Conjugate:Unconjugated
Cellular Localization:centrosome, chaperonin-containing T-complex, cytosol, extracellular exosome, Golgi apparatus
Calculated MW:60kDa
Observed MW:60kDa

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.

Purification Method:Affinity purification
Gene ID:6950
Clone Number:ARC0859
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Jurkat cells, using TCP1 alpha Rabbit mAb (CAB3887) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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