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TCF4/TCF7L2 Polyclonal Antibody (CAB20770)

SKU:
CAB20770
Product Type:
Antibody
Antibody Type:
Secondary Antibody
Host Species:
Goat
Isotype:
Rhodamine conjugated IgG
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TCF4/TCF7L2 Polyclonal Antibody
SKU:CAB20770
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 124-188 of human TCF4/TCF7L2 (NP_001354872.1).
Sequence:TART LHFQ SGST HYSA YKTI EHQI AVQY LQMK WPLL DVQA GSLQ SRQA LKDA RSPS PAHI VSNK V
Tested Applications:WB ELISA
Recommended Dilution:WB,1:100 - 1:500
Synonyms:TCF4; TCF-4; TCF4/TCF7L2
Positive Sample:SW620,Mouse brain
Conjugate:Unconjugated
Cellular Localization:nucleoplasm, nucleus, PML body
Calculated MW:68kDa
Observed MW:60kDa/75kDa

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:6934
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using TCF4/TCF7L2 antibody (CAB20770) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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