The TBX3 Monoclonal Antibody (CAB9646) is a valuable tool for researchers studying TBX3, a transcription factor with key roles in development and disease. This antibody, produced in mouse, exhibits high specificity for TBX3 in human samples and is suitable for use in applications such as Western blot and immunohistochemistry.TBX3 is a critical regulator of gene expression, influencing processes like cell proliferation, differentiation, and migration. Dysregulation of TBX3 has been linked to various diseases, including cancer and developmental disorders.
By targeting TBX3 with this antibody, researchers can investigate its functions in different cell types and explore its potential as a therapeutic target in disease treatments.The TBX3 Monoclonal Antibody offers a reliable tool for understanding the mechanisms governing TBX3 activity, paving the way for new insights into cellular processes and disease pathways. Its specificity and versatility make it an essential reagent for studies in molecular biology, developmental biology, and oncology.
Product Name:
Tbx3 Rabbit Monoclonal Antibody
SKU:
CAB9646
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 644-743 of human Tbx3 (O15119).
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.
Purification Method:
Affinity purification
Gene ID:
6926
Clone Number:
ARC1677
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Tbx3 antibody (CAB9646) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
