The TBR1 Polyclonal Antibody (CAB19550) is a valuable tool for researchers studying the T-box brain protein 1 (TBR1), a transcription factor essential for proper brain development and neural function. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the TBR1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in neurobiology and developmental disorders.
TBR1 plays a crucial role in the regulation of neuronal development and synaptic function, making it a key player in neurological disorders such as autism spectrum disorders and intellectual disabilities. Understanding the function and regulation of TBR1 is essential for uncovering the mechanisms underlying these conditions and developing potential therapeutic interventions. The TBR1 Polyclonal Antibody provides researchers with a reliable tool to explore the role of TBR1 in neurodevelopmental processes and neurological diseases.
Product Name:
TBR1 Rabbit Monoclonal Antibody
SKU:
CAB19550
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TBR1 (Q16650).
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
Purification Method:
Affinity purification
Gene ID:
10716
Clone Number:
ARC2198
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using TBR1 Rabbit mAb (CAB19550) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
