The TARBP2 Polyclonal Antibody (CAB9105) is a valuable tool for researchers studying TARBP2, a key protein involved in RNA interference pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the TARBP2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential reagent for studies in molecular biology and RNA regulation.TARBP2, also known as Trans-activation response RNA-binding protein 2, plays a crucial role in the processing of microRNAs and small interfering RNAs.
Its involvement in post-transcriptional gene silencing mechanisms makes it a significant target for research in RNA biology and gene regulation. Understanding the function of TARBP2 is essential for unraveling the complexities of RNA interference pathways and developing therapies targeting RNA-related diseases such as cancer and viral infections.
Product Name:
TARBP2 Rabbit Monoclonal Antibody
SKU:
CAB9105
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human TARBP2 (Q15633).
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
Purification Method:
Affinity purification
Gene ID:
6895
Clone Number:
ARC1792
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using TARBP2 Rabbit mAb (CAB9105) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
