The TARBP1 Monoclonal Antibody (CAB20524) is a valuable tool for researchers studying TARBP1, a key protein involved in RNA interference pathways. This antibody, produced using monoclonal technology, shows high specificity and sensitivity for detecting TARBP1 in human samples, making it suitable for use in applications such as Western blotting and immunofluorescence.TARBP1, also known as Trans-activation response RNA-binding protein 1, is essential for the processing of microRNA molecules and plays a critical role in gene regulation and cell function.
Dysregulation of TARBP1 has been implicated in various diseases, including cancer and viral infections. By targeting TARBP1 with this antibody, researchers can gain valuable insights into its function and potential therapeutic implications in these disease contexts.Overall, the TARBP1 Monoclonal Antibody (CAB20524) offers researchers a reliable and specific tool for studying TARBP1 in various biological processes, providing a deeper understanding of its role in health and disease.
Product Name:
TARBP1 Rabbit Polyclonal Antibody
SKU:
CAB20524
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1322-1621 of human TARBP1 (NP_005637.3).
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. This element forms a stable stem-loop structure and can be bound by either the protein encoded by this gene or by RNA polymerase II. This protein may act to disengage RNA polymerase II from TAR during transcriptional elongation. Alternatively spliced transcripts of this gene may exist, but their full-length natures have not been determined.
Purification Method:
Affinity purification
Gene ID:
6894
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TARBP1 antibody (CAB20524) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
