The TAPP1 Polyclonal Antibody (CAB20941) is a valuable tool for researchers studying TAPP1, a protein involved in intracellular signaling pathways. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to TAPP1, this antibody enables the detection and analysis of TAPP1 in a variety of cell types, making it an essential tool for investigations in cell signaling and signal transduction research.TAPP1 is known to play a crucial role in regulating cellular processes such as cell proliferation, survival, and differentiation through its interaction with various intracellular signaling molecules.
Understanding the function of TAPP1 is important for unraveling its contribution to normal cellular function as well as its potential role in diseases like cancer, diabetes, and neurodegenerative disorders. The TAPP1 Polyclonal Antibody provides researchers with a reliable means to investigate the role of TAPP1 in these contexts, ultimately leading to advancements in our understanding of cellular signaling pathways and potential therapeutic targets.
Product Name:
TAPP1 Monoclonal Antibody
SKU:
CAB20941
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-404 of human TAPP1 (Q9HB21).
This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.
Purification Method:
Affinity purification
Gene ID:
59338
Clone Number:
ARC2927
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates,using TAPP1 antibody (CAB20941) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
