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TACC3 Rabbit Monoclonal Antibody (CAB19617)

SKU:
CAB19617
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ERIC-1
ERIC1
€139 - €419
Frequently bought together:

Description

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TACC3 Rabbit Monoclonal Antibody (CAB19617)

The TACC3 Polyclonal Antibody (CAB19617) is a valuable tool for researchers studying the TACC3 protein, which is involved in cell division and microtubule organization. This antibody is produced in rabbits and has been validated for use in Western blot applications, allowing for the detection and analysis of TACC3 in various cell types.TACC3 plays a crucial role in ensuring proper cell division and has been linked to cancer development and progression.

By targeting TACC3 with this antibody, researchers can gain insights into its functions and potential therapeutic implications in cancer research.This antibody is highly reactive with human samples, making it suitable for studies in oncology and cell biology. Its specificity for TACC3 makes it an essential tool for understanding the molecular mechanisms driving cancer growth and metastasis.

Product Name:TACC3 Rabbit Monoclonal Antibody
SKU:CAB19617
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TACC3 (NP_006333.1).
Sequence:MSLQ VLND KNVS NEKN TENC DFLF SPPE VTGR SSVL RVSQ KENV PPKN LAKA MKVT FQTP LRDP QTHR ILSP SMAS KLEA PFTQ DDTL GLEN SHPV WTQK
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:ERIC1; Tacc4; ERIC-1; maskin; TACC3
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Cytosol, mitotic spindle, spindle pole
Calculated MW:90kDa
Observed MW:140kDa

TACC3, also known as ERIC 1, belongs to the TACC family. TACC family members TACC1, TACC2, and TACC3 map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 8, 10, and 4. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. It plays a role in the microtubule-dependent coupling of the nucleus and the centrosome and involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors.

Purification Method:Affinity purification
Gene ID:10460
Clone Number:ARC2195
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from 293T cells, using TACC3 Rabbit mAb (CAB19617) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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