The Syntaxin Polyclonal Antibody (CAB19813) is a valuable tool for researchers studying Syntaxin, a key protein involved in vesicle fusion and neurotransmitter release. This antibody, produced in rabbits, is specifically designed for detecting Syntaxin in various cell types, making it suitable for use in immunohistochemistry and immunofluorescence applications.Syntaxin is a crucial component of the SNARE complex, which mediates the fusion of vesicles with target membranes in neurons and other cell types. Its role in neurotransmission and intracellular membrane trafficking makes it an important target for studies in neuroscience and cell biology.
By using the Syntaxin Polyclonal Antibody, researchers can investigate the localization and expression levels of Syntaxin in different cellular compartments, providing insights into its function in physiological and pathological conditions.Overall, the Syntaxin Polyclonal Antibody offers a reliable tool for studying Syntaxin and its role in vesicle fusion, neurotransmitter release, and cellular trafficking processes. Its high specificity and sensitivity make it a valuable asset for researchers aiming to advance their understanding of neuronal communication and synaptic function.
Product Name:
Syntaxin Rabbit Monoclonal Antibody
SKU:
CAB19813
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Syntaxin (P61266).
axon, centrosome, cytoplasm, cytosol, microtubule organizing center, neuromuscular junction, nuclear lamina, nucleoplasm, nucleus, plasma membrane, presynaptic active zone membrane, SNARE complex, spindle, synaptic vesicle
Calculated MW:
33kDa
Observed MW:
35kDa
The protein encoded by this gene belongs to a family of proteins thought to play a role in the exocytosis of synaptic vesicles. Vesicle exocytosis releases vesicular contents and is important to various cellular functions. For instance, the secretion of transmitters from neurons plays an important role in synaptic transmission. After exocytosis, the membrane and proteins from the vesicle are retrieved from the plasma membrane through the process of endocytosis. Mutations in this gene have been identified as one cause of fever-associated epilepsy syndromes. A possible link between this gene and Parkinson's disease has also been suggested. [provided by RefSeq, Jan 2015]
Purification Method:
Affinity purification
Gene ID:
6804/112755/2054/6809
Clone Number:
ARC2339
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Syntaxin Rabbit mAb (CAB19813) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
