Synapsin II Rabbit Monoclonal Antibody (CAB19542)
- SKU:
- CAB19542
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SYNII
Description
Product Name: | Synapsin II Rabbit Monoclonal Antibody |
SKU: | CAB19542 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human Synapsin II (Q92777). |
Sequence: | HLII GMQY AGLP SINS LESI YNFC DKPW VFAQ LVAI YKTL GGEK FPLI EQTY YPNH KEML TLPT FPVV VKIG HAHS GMGK VKVE NHYD FQDI ASVV ALTQ T |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | SYNII; Synapsin II |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Glutamatergic synapse, Plasma membrane, Postsynaptic density, Schaffer collateral - CA1 synapse, SNARE complex, Synapse, Synaptic vesicle membrane |
Calculated MW: | 63kDa |
Observed MW: | 60kDa |
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite direction.
Purification Method: | Affinity purification |
Gene ID: | 6854 |
Clone Number: | ARC2166 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |