The SYK Polyclonal Antibody (CAB2123) is specifically designed for research involving SYK, a key protein in the regulation of immune response and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SYK protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in immunology and cancer research.SYK, also known as spleen tyrosine kinase, plays a crucial role in immune signaling pathways and is involved in cell activation and proliferation. Dysregulation of SYK has been implicated in various diseases, including autoimmune disorders and certain types of cancer.
Therefore, investigating the function and expression of SYK is essential for understanding the underlying mechanisms of these conditions and developing targeted therapies.By utilizing the SYK Polyclonal Antibody (CAB2123), researchers can gain valuable insights into the role of SYK in immune regulation and disease pathogenesis. This antibody provides a reliable tool for studying SYK expression levels and activity, paving the way for advancements in the field of immunology and potential therapeutic interventions.
Product Name:
Syk Rabbit Polyclonal Antibody
SKU:
CAB2123
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human Syk (NP_001128524.1).
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6850
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Daudi, using Syk Rabbit pAb (CAB2123) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
