The Anti-SULT2A1 Antibody (CAB8334) is a powerful tool for researchers studying SULT2A1, an important enzyme involved in the metabolism of various compounds in the body. This polyclonal antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. SULT2A1, also known as sulfotransferase 2A1, plays a crucial role in the sulfation of steroids and bile acids, contributing to the regulation of hormone levels and detoxification processes. Dysregulation of SULT2A1 has been implicated in various diseases, including liver disorders, metabolic syndromes, and certain types of cancer.
By targeting the SULT2A1 protein, this antibody enables researchers to detect and analyze its expression in different cell types, providing valuable insights into its function and potential role in disease development. Its utility in studying SULT2A1 makes it an essential tool for research in pharmacology, toxicology, and endocrinology. Unlocking the mechanisms underlying SULT2A1 activity could lead to the development of novel therapeutic approaches for a range of health conditions.
Product Name:
SULT2A1 Rabbit Monoclonal Antibody
SKU:
CAB8334
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-285 of human SULT2A1 (Q06520).
This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome.
Purification Method:
Affinity purification
Gene ID:
6822
Clone Number:
ARC1853
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Hep G2 cells, using SULT2A1 antibody (CAB8334) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
