The Anti-STX1A Antibody (CAB19243) is a valuable tool for researchers studying STX1A, a protein involved in neuronal signaling and synaptic transmission. This antibody, generated in rabbits, is highly specific to human samples and is suitable for use in various applications, including Western blotting and immunofluorescence.STX1A is a key player in neuronal communication, facilitating the release of neurotransmitters at synaptic terminals. Dysregulation of STX1A function has been implicated in neurological disorders such as epilepsy, Alzheimer's disease, and Parkinson's disease.
By targeting STX1A with this antibody, researchers can gain insight into its role in these conditions and potentially identify new therapeutic targets.The Anti-STX1A Antibody is a reliable tool for scientists investigating the complex mechanisms of neuronal communication and the pathophysiology of neurological diseases. Its high specificity and sensitivity make it a valuable asset for studies focusing on synaptic function and dysfunction.
Product Name:
STX1A Rabbit Monoclonal Antibody
SKU:
CAB19243
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human STX1A (Q16623).
Cell junction, Cell membrane, Cytoplasmic vesicle, Secreted, Single-pass type IV membrane protein, Secretory vesicle, Synapse, Synaptic vesicle membrane, Synaptosome.
Calculated MW:
33kDa
Observed MW:
33kDa
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6804
Clone Number:
ARC2403
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat brain, using STX1A Rabbit mAb (CAB19243) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
