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STK36 Rabbit Polyclonal Antibody (CAB10974)

SKU:
CAB10974
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
STK36
FU
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:STK36 Rabbit Polyclonal Antibody
SKU:CAB10974
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 250-450 of human STK36 (NP_056505.2).
Sequence:YHPF IAGH VTII TEPA GPDL GTPF TSRL PPEL QVLK DEQA HRLA PKGN QSRI LTQA YKRM AEEA MQKK HQNT GPAL EQED KTSK VAPG TAPL PRLG ATPQ ESSL LAGI LASE LKSS WAKS GTGE VPSA PREN RTTP DCER AFPE ERPE VLGQ RSTD VVDL ENEE PDSD NEWQ HLLE TTEP VPIQ LKAP LTLL CNPD FCQR I
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:FU; CILD46; STK36
Positive Sample:Mouse brain,Mouse testis
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:144kDa
Observed MW:144kDa

This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:27148
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using STK36 Rabbit pAb (CAB10974) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.

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