STK33 Rabbit Monoclonal Antibody (CAB19803)
- SKU:
- CAB19803
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Product Name: | STK33 Rabbit Monoclonal Antibody |
SKU: | CAB19803 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 399-514 of human STK33 (Q9BYT3). |
Sequence: | KEWK NNPE SVEE NTTE EKNK PSTE EKLK SYQP WGNV PDAN YTSD EEEE KQST AYEK QFPA TSKD NFDM CSSS FTSS KLLP AEIK GEME KTPV TPSQ GTAT KYPA KSGA LSRT KKKL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | STK33 |
Positive Sample: | SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, nucleus, perinuclear region of cytoplasm |
Calculated MW: | 58kDa |
Observed MW: | 65kDa |
Serine/threonine protein kinase (STK33) is a 524-residue kinase that belongs to the calcium/calmodulin-dependent family of kinases. STK33 exhibits differential expression in normal and malignant cancer tissue, including hepatocellular carcinoma. STK33 expression is required in the context of mutant KRAS, the most commonly mutated human oncogene, to maintain for cellular viability and proliferation. STK33 depletion via modulation of interacting proteins results in proteasome-mediated degradation of STK33 in human cancer cells, triggering apoptosis.
Purification Method: | Affinity purification |
Gene ID: | 65975 |
Clone Number: | ARC2330 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |