STIP1 Rabbit Monoclonal Antibody (CAB0036)
- SKU:
- CAB0036
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HEL-S-94n
- HOP
- IEF-SSP-3521
- P60
- STI1
- STI1L
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | STIP1 Rabbit Monoclonal Antibody |
SKU: | CAB0036 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-98 of human STIP1 (P31948). |
Sequence: | EQVN ELKE KGNK ALSV GNID DALQ CYSE AIKL DPHN HVLY SNRS AAYA KKGD YQKA YEDG CKTV DLKP DWGK GYSR KAAA LEFL NRFE EAKR TYEE G |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521; STIP1 |
Positive Sample: | A-549,NIH/3T3,Mouse testis,Mouse brain,Rat brain,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 63kDa |
Observed MW: | 68kDa |
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).
Purification Method: | Affinity purification |
Gene ID: | 10963 |
Clone Number: | ARC1805 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |