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STIP1 Rabbit Monoclonal Antibody (CAB0036)

SKU:
CAB0036
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
HEL-S-94n
HOP
IEF-SSP-3521
P60
STI1
STI1L
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:STIP1 Rabbit Monoclonal Antibody
SKU:CAB0036
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 2-98 of human STIP1 (P31948).
Sequence:EQVN ELKE KGNK ALSV GNID DALQ CYSE AIKL DPHN HVLY SNRS AAYA KKGD YQKA YEDG CKTV DLKP DWGK GYSR KAAA LEFL NRFE EAKR TYEE G
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200
Synonyms:HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521; STIP1
Positive Sample:A-549,NIH/3T3,Mouse testis,Mouse brain,Rat brain,Rat thymus
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:63kDa
Observed MW:68kDa

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).

Purification Method:Affinity purification
Gene ID:10963
Clone Number:ARC1805
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using STIP1 Rabbit mAb (CAB0036) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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