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STING Rabbit Polyclonal Antibody (CAB20175)

SKU:
CAB20175
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ERIS
MPYS
Mita
STING
Tmem173
STING-beta
2610307O08Rik
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:STING Rabbit Polyclonal Antibody
SKU:CAB20175
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 280-371 of mouse STING. (NP_938023.1).
Sequence:SRED RLEQ AKLF CRTL EDIL ADAP ESQN NCRL IAYQ EPAD DSSF SLSQ EVLR HLRQ EEKE EVTV GSLK TSAV PSTS TMSQ EPEL LISG MEKP
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:ERIS; MPYS; Mita; STING; Tmem173; STING-beta; 2610307O08Rik
Positive Sample:293T,A-549,RAW264.7
Conjugate:Unconjugated
Cellular Localization:autophagosome, cytoplasm, cytosol, endoplasmic reticulum, endosome, Golgi apparatus, mitochondrial outer membrane, nucleoplasm, perinuclear region of cytoplasm, peroxisome, plasma membrane
Calculated MW:43kDa
Observed MW:33kDa/35kDa

Enables 2',3'-cyclic GMP-AMP binding activity; cyclic-di-GMP binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including defense response to other organism; macroautophagy; and positive regulation of interferon-beta production. Acts upstream of or within cellular response to interferon-beta; positive regulation of transcription by RNA polymerase II; and regulation of inflammatory response. Located in several cellular components, including autophagosome; perinuclear region of cytoplasm; and peroxisome. Is expressed in ductus deferens; epididymis; ileum; and prostate gland. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1).

Purification Method:Affinity purification
Gene ID:72512
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using STING Rabbit pAb (CAB20175) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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