The SSTR2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0272) is a cutting-edge tool designed for research involving the somatostatin receptor type 2 (SSTR2), a key player in neuroendocrine signaling and tumor suppression. This antibody, generated in rabbits, offers high specificity and sensitivity in detecting SSTR2 protein expression in human samples, making it an essential tool for immunohistochemistry and immunofluorescence studies.SSTR2 is a G-protein coupled receptor that plays a crucial role in mediating the effects of somatostatin, a hormone involved in regulating hormone secretion, cell proliferation, and neurotransmission. Dysregulation of SSTR2 has been implicated in various cancers, neuroendocrine tumors, and neurological disorders, making it a promising target for therapeutic interventions.
By using the SSTR2 Chimeric Recombinant Rabbit Monoclonal Antibody, researchers can gain valuable insights into the expression levels and localization of SSTR2 in different tissues and cell types, facilitating the study of somatostatin signaling pathways and the development of novel strategies for diagnosing and treating SSTR2-related diseases. Its exceptional performance and specificity make it an indispensable tool for advancing research in areas such as oncology, endocrinology, and neuroscience.
SKU:
HDAB0272
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC428
Synonyms:
SRIF-1, SS2R
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney.
