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SRGAP2 Rabbit Polyclonal Antibody (CAB19512)

SKU:
CAB19512
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
SRGAP2
ARHGAP34
FNBP2
SRGAP2A
SRGAP3
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SRGAP2 Rabbit Polyclonal Antibody
SKU:CAB19512
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 790-900 of human SRGAP2 (NP_056141.2).
Sequence:GVVE RSSP KSEI EVIS EPPE EKVT ARAG ASCP SGGH VADI YLAN INKQ RKRP ESGS IRKT FRSD SHGL SSSL TDSS SPGV GASC RPSS QPIM SQSL PKEG PDKC SISG HGS
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:FNBP2; SRGAP3; SRGAP2A; ARHGAP34; SRGAP2
Positive Sample:Mouse brain
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Nucleus, dendritic spine, lamellipodium, phagosome, postsynaptic cell membrane, postsynaptic density, synapse.
Calculated MW:121kDa
Observed MW:140kDa

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.

Purification Method:Affinity purification
Gene ID:23380
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SRGAP2 Rabbit pAb (CAB19512) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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