SRGAP2 Rabbit Polyclonal Antibody (CAB19512)
- SKU:
- CAB19512
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SRGAP2
- ARHGAP34
- FNBP2
- SRGAP2A
- SRGAP3
Frequently bought together:
Description
Product Name: | SRGAP2 Rabbit Polyclonal Antibody |
SKU: | CAB19512 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 790-900 of human SRGAP2 (NP_056141.2). |
Sequence: | GVVE RSSP KSEI EVIS EPPE EKVT ARAG ASCP SGGH VADI YLAN INKQ RKRP ESGS IRKT FRSD SHGL SSSL TDSS SPGV GASC RPSS QPIM SQSL PKEG PDKC SISG HGS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | FNBP2; SRGAP3; SRGAP2A; ARHGAP34; SRGAP2 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Nucleus, dendritic spine, lamellipodium, phagosome, postsynaptic cell membrane, postsynaptic density, synapse. |
Calculated MW: | 121kDa |
Observed MW: | 140kDa |
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.
Purification Method: | Affinity purification |
Gene ID: | 23380 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |