The SPATA5 Polyclonal Antibody (CAB20494) is specifically designed for research involving SPATA5, a protein involved in spermatogenesis and fertilization. This antibody, generated in rabbits, exhibits high affinity and specificity towards SPATA5 in human samples, making it a reliable tool for Western blot applications. By targeting the SPATA5 protein, researchers can investigate its functions and mechanisms in various reproductive processes, providing insights into male fertility and potential therapeutic targets for infertility-related conditions.
SPATA5, also known as Spermatogenesis-associated protein 5, plays a crucial role in the development and maturation of sperm cells, making it a key player in male reproductive health. Understanding the molecular pathways and interactions involving SPATA5 can offer valuable information for studying infertility, reproductive disorders, and potential interventions to improve fertility outcomes. The SPATA5 Polyclonal Antibody is a valuable resource for researchers in the fields of reproductive biology, embryology, and fertility research.
Product Name:
SPATA5 Rabbit Polyclonal Antibody
SKU:
CAB20494
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 228-304 of human SPATA5 (NP_001304728).
This gene encodes a member of the ATPase associated with diverse activities family, whose members are defined by a highly conserved ATPase domain. Members of this family participate in diverse cellular processes that include membrane fusion, DNA replication, microtubule severing, and protein degradation. The protein encoded by this gene has a putative mitochondrial targeting sequence and has been proposed to function in maintenance of mitochondrial function and integrity during mouse spermatogenesis. Allelic variants in this gene have been associated with epilepsy, hearing loss, and cognitive disability syndrome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
166378
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of 293T cells, using SPATA5 antibody (CAB20494) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
