SOX10 Rabbit Monoclonal Antibody (CAB8655)
- SKU:
- CAB8655
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DOM
- PCWH
- WS2E
- WS4
- WS4C
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Product Name: | SOX10 Rabbit Monoclonal Antibody |
| SKU: | CAB8655 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse,Rat |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human SOX10 (P56693). |
| Sequence: | VDAK AQVK TETA GPQG PPHY TDQP STSQ IAYT SLSL PHYG SAFP SISR PQFD YSDH QPSG PYYG HSGQ ASGL YSAF SYMG PSQR PLYT AISD PSPS GPQS H |
| Tested Applications: | WB IF/ICC ELISA |
| Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
| Synonyms: | DOM; WS4; PCWH; WS2E; WS4C; SOX-10; SOX10 |
| Positive Sample: | HeLa,HT-29,SH-SY5Y,Mouse large intestine,Mouse brain,Mouse heart,Rat brain,Rat heart |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm, Nucleus, Mitochondrion outer membrane |
| Calculated MW: | 50kDa |
| Observed MW: | 62kDa |
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
| Purification Method: | Affinity purification |
| Gene ID: | 6663 |
| Clone Number: | ARC1767 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates using SOX10 Rabbit mAb (CAB8655) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s. |
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