The SNX1 Polyclonal Antibody (CAB3398) is a valuable tool for researchers studying SNX1, a protein involved in cell trafficking and sorting. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in Western blot applications. By targeting the SNX1 protein, this antibody allows for the detection and analysis of SNX1 in various cell types, making it an essential resource for studies in cell biology, membrane trafficking, and vesicular transport.SNX1 is a key player in the process of endosomal sorting and recycling, regulating the trafficking of proteins within cells.
Dysfunction of SNX1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic conditions. Investigating the role of SNX1 with this antibody can provide valuable insights into cellular mechanisms and potential therapeutic targets for these diseases.Overall, the SNX1 Polyclonal Antibody (CAB3398) is a reliable tool for researchers looking to explore the functions of SNX1 in health and disease. Its specificity and sensitivity make it an ideal choice for experiments aimed at unraveling the intricate processes of cellular trafficking and sorting.
Product Name:
SNX1 Rabbit Monoclonal Antibody
SKU:
CAB3398
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SNX1 (Q13596).
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
6642
Clone Number:
ARC1969
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SNX1 Rabbit mAb (CAB3398) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
