The Anti-SNRPA1 Antibody (CAB0647) is a high-quality polyclonal antibody designed for research involving the SNRPA1 protein. SNRPA1, also known as U1 small nuclear ribonucleoprotein A, is a key component of the spliceosome complex involved in pre-mRNA splicing. This antibody is raised in rabbits and is highly reactive with human samples. It has been validated for use in Western blot applications, allowing for the detection and analysis of SNRPA1 in various cell types. This makes it an ideal tool for studies in molecular biology and RNA splicing mechanisms.
The SNRPA1 protein is essential for the proper splicing of pre-mRNA and its dysregulation has been implicated in various diseases, including cancer and autoimmune disorders. Understanding the role of SNRPA1 in splicing can provide valuable insights into disease mechanisms and potential therapeutic targets. This antibody is a valuable resource for researchers studying RNA splicing and its impact on human health.
Product Name:
SNRPA1 Rabbit Monoclonal Antibody
SKU:
CAB0647
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 156-255 of human SNRPA1 (P09661).
Enables RNA binding activity. Involved in mRNA splicing, via spliceosome and spermatogenesis. Located in nuclear speck. Part of U2-type catalytic step 2 spliceosome and U2-type precatalytic spliceosome. Implicated in connective tissue disease.
Purification Method:
Affinity purification
Gene ID:
6627
Clone Number:
ARC2532
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SNRPA1 Rabbit mAb (CAB0647) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
