SMURF2 Rabbit Monoclonal Antibody (CAB2278)
- SKU:
- CAB2278
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SMURF2
- E3 ubiquitin-protein ligase SMURF2
Frequently bought together:
Description
Product Name: | SMURF2 Rabbit Monoclonal Antibody |
SKU: | CAB2278 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 201-290 of human SMURF2 (Q9HAU4). |
Sequence: | PLSC FVDE NTPI SGTN GATC GQSS DPRL AERR VRSQ RHRN YMSR THLH TPPD LPEG YEQR TTQQ GQVY FLHT QTGV STWH DPRV PRDL SN |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 400μg-600μg extracts of whole cells |
Synonyms: | SMURF2; E3 ubiquitin-protein ligase SMURF2 |
Positive Sample: | U2OS,MCF7,SH-SY5Y,Mouse lung,Mouse testis,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Membrane raft, Nucleus. |
Calculated MW: | 86kDa |
Observed MW: | 80kDa |
Enables SMAD binding activity; identical protein binding activity; and ubiquitin-protein transferase activity. Involved in negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of trophoblast cell migration; and ubiquitin-dependent SMAD protein catabolic process. Located in nuclear speck. Part of ubiquitin ligase complex.
Purification Method: | Affinity purification |
Gene ID: | 64750 |
Clone Number: | ARC1897 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |