The Anti-SMURF2 Antibody (CAB2278) is a valuable tool for researchers studying SMURF2, a protein involved in cellular processes such as ubiquitin-mediated protein degradation and cell signaling. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the SMURF2 protein, this antibody enables the detection and analysis of SMURF2 expression levels in various cell types.SMURF2 is known for its role in regulating diverse cellular functions, including cell proliferation, differentiation, and apoptosis. Dysfunction of SMURF2 has been implicated in various diseases, making it a potential target for therapeutic interventions.
Investigating the function of SMURF2 can provide valuable insights into the underlying mechanisms of diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases.With its specificity and sensitivity, the Anti-SMURF2 Antibody (CAB2278) is a valuable tool for researchers seeking to unravel the intricate roles of SMURF2 in cellular physiology and disease pathogenesis. Its application in immunology and cancer research makes it an essential component of studies aiming to elucidate the complex interplay between SMURF2 and disease processes.
Product Name:
SMURF2 Rabbit Monoclonal Antibody
SKU:
CAB2278
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 201-290 of human SMURF2 (Q9HAU4).
Enables SMAD binding activity; identical protein binding activity; and ubiquitin-protein transferase activity. Involved in negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of trophoblast cell migration; and ubiquitin-dependent SMAD protein catabolic process. Located in nuclear speck. Part of ubiquitin ligase complex.
Purification Method:
Affinity purification
Gene ID:
64750
Clone Number:
ARC1897
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using SMURF2 Rabbit mAb (CAB2278) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
