The Anti-SMC4 Antibody (CAB3559) offered by AssayGenie is a high-quality polyclonal antibody designed for research involving SMC4, a component of the cohesin complex essential for chromosome segregation and DNA repair. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in Western blot and immunofluorescence applications.SMC4, also known as structural maintenance of chromosomes 4, plays a crucial role in maintaining genome stability and proper chromosome organization. Dysregulation of SMC4 has been implicated in various diseases, including cancer and developmental disorders.
The Anti-SMC4 Antibody allows for the detection and analysis of SMC4 protein levels in different cell types, making it a valuable tool for studies in cell biology, genetics, and oncology research.Understanding the function and regulation of SMC4 is essential for uncovering its role in cellular processes and disease development. The Anti-SMC4 Antibody provides researchers with a reliable tool to investigate the biological functions of SMC4 and its potential implications in human health and disease.
Product Name:
SMC4 Rabbit Monoclonal Antibody
SKU:
CAB3559
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1189-1288 of human SMC4 (Q9NTJ3).
This gene belongs to the 'structural maintenance of chromosomes' (SMC) gene family. Members of this gene family play a role in two changes in chromosome structure during mitotic segregation of chromosomes- chromosome condensation and sister chromatid cohesion. The protein encoded by this gene is likely a subunit of the 13S condensin complex, which is involved in chromosome condensation. A pseudogene related to this gene is located on chromosome 2.
Purification Method:
Affinity purification
Gene ID:
10051
Clone Number:
ARC2042
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SMC4 Rabbit mAb (CAB3559) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
