Slit2 Rabbit Monoclonal Antibody (CAB3467)
- SKU:
- CAB3467
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SLIL3
- Slit-2
Description
Product Name: | Slit2 Rabbit Monoclonal Antibody |
SKU: | CAB3467 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1400-1500 of human Slit2 (O94813). |
Sequence: | GHGG VLCD EEED LFNP CQAI KCKH GKCR LSGL GQPY CECS SGYT GDSC DREI SCRG ERIR DYYQ KQQG YAAC QTTK KVSR LECR GGCA GGQC CGPL RSKR R |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | SLIL3; Slit-2; Slit2 |
Positive Sample: | 293T,PC-3,Mouse lung,Mouse brain,Mouse kidney,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 170kDa |
Observed MW: | 200kDa |
This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 9353 |
Clone Number: | ARC2010 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |