The SLFN12 Monoclonal Antibody (CAB20166) is a vital tool for researchers studying SLFN12, a protein involved in various cellular processes, including DNA repair and replication. This antibody, generated in mice, specifically targets SLFN12 in human samples and is validated for use in applications such as immunofluorescence and flow cytometry.SLFN12, a member of the Schlafen family of proteins, is known for its role in regulating DNA damage response and influencing cell proliferation.
Dysregulation of SLFN12 has been linked to cancer progression and resistance to certain chemotherapeutic agents, making it an important target for research in oncology. By using the SLFN12 Monoclonal Antibody, researchers can investigate the function and expression of SLFN12 in different cell types, aiding in the understanding of its biological significance and potential therapeutic implications.
Product Name:
SLFN12 Rabbit Polyclonal Antibody
SKU:
CAB20166
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 320-390 of human SLFN12 (NP_001275938.1).
Predicted to act upstream of or within negative regulation of cell population proliferation.
Purification Method:
Affinity purification
Gene ID:
55106
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells, using SLFN12 Rabbit pAb (CAB20166) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
