The SLFN11 Monoclonal Antibody (CAB20809) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human SLFN11 and has been rigorously validated for use in Western blot and immunohistochemistry applications.SLFN11 is known for its role in regulating cellular response to chemotherapy and radiation therapy, making it a promising target for cancer treatment research. By enabling the detection and analysis of SLFN11 in various cell types, this antibody is essential for understanding the mechanisms underlying drug sensitivity and resistance in cancer cells.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
SLFN11 Monoclonal Antibody
SKU:
CAB20809
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC51651
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SLFN8/9, SLFN11
Positive Sample:
Jurkat
Cellular Localization:
Cytosol, Nucleoplasm, Nucleus.
Calculated MW:
103kDa
Observed MW:
101kDa
Enables tRNA binding activity. Involved in several processes, including defense response to virus; negative regulation of G1/S transition of mitotic cell cycle; and replication fork arrest. Located in cytosol; nucleoplasm; and site of DNA damage.
Purification Method
Affinity purification
Gene ID
91607
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Jurkat cells, using SLFN11 Rabbit mAb (CAB20809) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
