The SLC5A2 Monoclonal Antibody (CAB20271) is a valuable tool for researchers studying SLC5A2, a membrane transporter protein involved in glucose and sodium reabsorption in the kidney. This antibody, produced using hybridoma technology, exhibits high specificity for human samples and is suitable for use in applications such as immunohistochemistry and flow cytometry.SLC5A2, also known as sodium-glucose cotransporter 2, is a key player in glucose homeostasis and renal function. Dysregulation of SLC5A2 has been implicated in conditions such as diabetes and renal disorders, making it a target of interest for therapeutic interventions.
By targeting SLC5A2 with this monoclonal antibody, researchers can gain insights into its function and potential implications for disease management. Investigating the role of SLC5A2 using this antibody may lead to advancements in understanding glucose metabolism, kidney function, and the development of novel treatment strategies for metabolic and renal diseases. Whether studying basic biology or therapeutic applications, the SLC5A2 Monoclonal Antibody is a valuable tool for researchers in the fields of physiology, metabolism, and nephrology.
Product Name:
SLC5A2 Rabbit Polyclonal Antibody
SKU:
CAB20271
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 564-624 of human SLC5A2 (NP_003032.1).
Sequence:
RHSK EERE DLDA DEQQ GSSL PVQN GCPE SAME MNEP QAPA PSLF RQCL LWFC GMSR GGVG S
This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6524
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC5A2 Rabbit pAb (CAB20271) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 45s.