The SLC3A2/CD98hc Polyclonal Antibody (CAB3658) is a vital tool for research involving the SLC3A2/CD98hc protein, a cell surface molecule known for its role in amino acid transport and cell adhesion. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been extensively validated for use in Western blot applications. By binding to the SLC3A2/CD98hc protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable resource for studies in the fields of molecular biology, biochemistry, and cancer research.
SLC3A2/CD98hc, also referred to as a multifunctional amino acid transporter protein, plays a key role in amino acid uptake and cellular signaling pathways. Its involvement in essential cellular processes makes it a promising target for investigation in diseases like cancer, metabolic disorders, and neurological conditions. Understanding the function of SLC3A2/CD98hc is crucial for advancing research and potentially developing targeted therapies aimed at modulating amino acid transport and cell growth regulation.
Product Name:
CD98 Rabbit Monoclonal Antibody
SKU:
CAB3658
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human SLC3A2/CD98hc (P08195).
This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
6520
Clone Number:
ARC0816
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using antibody (CAB3658) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
