The Anti-SLC39A11 Antibody (CAB20338) is a highly specific tool for research involving SLC39A11, a zinc transporter protein that plays a crucial role in cellular zinc homeostasis. This polyclonal antibody, produced in rabbits, is validated for use in various applications such as Western blot, immunoprecipitation, and immunofluorescence.SLC39A11, also known as ZIP11, is essential for maintaining zinc balance in cells and is involved in processes such as cell proliferation, differentiation, and immune response. Dysregulation of SLC39A11 has been linked to various diseases, including cancer, neurodegenerative disorders, and diabetes, making it a promising target for therapeutic intervention.
By targeting SLC39A11 with this antibody, researchers can investigate the expression levels and localization of the protein in different cell types and tissues, shedding light on its role in disease pathology and potential therapeutic strategies. Overall, the Anti-SLC39A11 Antibody (CAB20338) is a valuable tool for advancing our understanding of zinc homeostasis and its impact on human health.
Product Name:
Slc39a11 Rabbit Polyclonal Antibody
SKU:
CAB20338
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 101-174 of mouse Slc39a11 (NP_001159975.1).
Sequence:
HLGA TEDP QTAL ALNL DPAL MKKS DPRD PTSL LFPE SELS IRIG STGL LSDK RENG EVYQ RKKV AATD LAEG VA
Enables zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to act upstream of or within zinc ion transport. Located in Golgi apparatus; nucleus; and plasma membrane. Orthologous to human SLC39A11 (solute carrier family 39 member 11).
Purification Method:
Affinity purification
Gene ID:
69806
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Slc39a11 Rabbit pAb (CAB20338) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
