The SLBP Polyclonal Antibody (CAB20178) is a valuable tool for researchers studying the function of SLBP, a key protein involved in RNA metabolism and processing. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.SLBP, also known as Stem-loop binding protein, plays a crucial role in the regulation of mRNA translation and stability, making it essential for proper gene expression. Studies have shown that abnormal SLBP expression is associated with various diseases, including cancer and developmental disorders.
By targeting the SLBP protein, researchers can gain insights into its role in RNA processing and its implications in disease pathology. This antibody enables the detection and analysis of SLBP in different cell types, facilitating investigations into RNA metabolism, gene regulation, and potential therapeutic interventions in conditions affected by dysregulated SLBP activity.
Product Name:
SLBP Rabbit Polyclonal Antibody
SKU:
CAB20178
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 125-223 of human SLBP (NP_006518.1).
This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.
Purification Method:
Affinity purification
Gene ID:
7884
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse testis, using SLBP Rabbit pAb (CAB20178) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
