SIRT2 Rabbit Monoclonal Antibody (CAB3967)
- SKU:
- CAB3967
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SIR2
- SIR2L
- SIR2L2
Frequently bought together:
Description
Product Name: | SIRT2 Rabbit Monoclonal Antibody |
SKU: | CAB3967 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SIRT2 (Q8IXJ6). |
Sequence: | MAEP DPSH PLET QAGK VQEA QDSD SDSE GGAA GGEA DMDF LRNL FSQT LSLG SQKE RLLD ELTL EGVA RYMQ SERC RRVI CLVG AGIS TSAG IPDF RSPS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | SIR2; SIR2L; SIR2L2; SIRT2 |
Positive Sample: | HeLa,293T,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | centriole, centrosome, cytoplasm, cytosol, glial cell projection, growth cone, lateral loop, meiotic spindle, mitochondrion, mitotic spindle, myelin sheath, nucleolus, nucleus, paranodal junction, perikaryon, perinuclear region of cytoplasm, plasma membrane, spindle |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
Purification Method: | Affinity purification |
Gene ID: | 22933 |
Clone Number: | ARC2644 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |