SHH Rabbit Polyclonal Antibody (CAB18863)
- SKU:
- CAB18863
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- 9530036O11Rik
- Dsh
- Hhg1
- Hx
- Hxl3
- M100081
Description
Product Name: | SHH Rabbit Polyclonal Antibody |
SKU: | CAB18863 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 187-281 of mouse SHH (NP_033196.1). |
Sequence: | KAEN SVAA KSGG CFPG SATV HLEQ GGTK LVKD LRPG DRVL AADD QGRL LYSD FLTF LDRD EGAK KVFY VIET LEPR ERLL LTAA HLLF VAPH NDS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | Hx; Dsh; Hhg1; Hxl3; ShhNC; M100081; 9530036O11Rik; SHH |
Positive Sample: | A-549,Mouse lung,Mouse brain,Rat lung |
Cellular Localization: | axon, dendrite, endoplasmic reticulum, extracellular region, extracellular space, Golgi apparatus, nucleus, plasma membrane, synaptic vesicle |
Calculated MW: | 48kDa |
Observed MW: | 45kDa |
Enables glycosaminoglycan binding activity; laminin-1 binding activity; and patched binding activity. Involved in several processes, including hematopoietic or lymphoid organ development; positive regulation of T cell activation; and regulation of smooth muscle cell differentiation. Acts upstream of or within several processes, including animal organ development; limb morphogenesis; and neurogenesis. Located in several cellular components, including cell surface; extracellular space; and membrane raft. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb bud; and sensory organ. Used to study brachydactyly type A1 and holoprosencephaly 3. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; holoprosencephaly (multiple); hypoplastic or aplastic tibia with polydactyly; middle cerebral artery infarction; and polydactyly. Orthologous to human SHH (sonic hedgehog signaling molecule).
Purification Method: | Affinity purification |
Gene ID: | 20423 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |