SF3B1 Rabbit Monoclonal Antibody (CAB9737)
- SKU:
- CAB9737
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- Hsh155
- MDS
- PRP10
- PRPF10
- SAP155
- SF3b155
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SF3B1 Rabbit Monoclonal Antibody |
SKU: | CAB9737 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SF3B1 (O75533). |
Sequence: | MAKI AKTH EDIE AQIR EIQG KKAA LDEA QGVG LDST GYYD QEIY GGSD SRFA GYVT SIAA TELE DDDD DYSS STSL LGQK KPGY HAPV ALLN DIPQ STEQ |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | MDS; PRP10; Hsh155; PRPF10; SAP155; SF3b155; SF3B1 |
Positive Sample: | HeLa,NIH/3T3,Jurkat,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | B-WICH complex, Nuclear speck, Nucleolus, Nucleoplasm, Nucleus |
Calculated MW: | 146kDa |
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 23451 |
Clone Number: | ARC1724 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |