The SETD1B Polyclonal Antibody (CAB20155) is a valuable tool for researchers studying SETD1B, a histone methyltransferase involved in gene regulation and chromatin remodeling. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.SETD1B plays a crucial role in epigenetic regulation by methylating histone proteins, ultimately influencing gene expression patterns. Dysregulation of SETD1B has been implicated in various diseases, including cancer and developmental disorders.
Thus, understanding the function and expression of SETD1B is essential for unraveling its contributions to disease pathology and potential therapeutic interventions.The SETD1B Polyclonal Antibody (CAB20155) offers a reliable tool for detecting and analyzing SETD1B expression in different cell types and tissues, making it an ideal choice for researchers exploring the role of histone methyltransferases in health and disease.
Product Name:
SETD1B Rabbit Polyclonal Antibody
SKU:
CAB20155
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1673-1770 of human SETD1B (NP_001340274.1).
SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al., 2007 [PubMed 17355966]).
Purification Method:
Affinity purification
Gene ID:
23067
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using SETD1B Rabbit pAb (CAB20155) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
