SERCA1/ATP2A1 Rabbit Monoclonal Antibody (CAB19639)
- SKU:
- CAB19639
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ATP2A
- SERCA1
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SERCA1/ATP2A1 Rabbit Monoclonal Antibody |
SKU: | CAB19639 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 900-1001 of human SERCA1/ATP2A1 (O14983). |
Sequence: | ALSV LVTI EMCN ALNS LSEN QSLL RMPP WVNI WLLG SICL SMSL HFLI LYVD PLPM IFKL RALD LTQW LMVL KISL PVIG LDEI LKFV ARNY LEDP EDER RK |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | ATP2A; SERCA1; SERCA1/ATP2A1 |
Positive Sample: | Mouse skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Sarcoplasmic reticulum membrane |
Calculated MW: | 95kDa/110kDa |
Observed MW: | 110kDa |
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 487 |
Clone Number: | ARC2207 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |