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SERCA1/ATP2A1 Rabbit Monoclonal Antibody (CAB19639)

SKU:
CAB19639
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ATP2A
SERCA1
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SERCA1/ATP2A1 Rabbit Monoclonal Antibody
SKU:CAB19639
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 900-1001 of human SERCA1/ATP2A1 (O14983).
Sequence:ALSV LVTI EMCN ALNS LSEN QSLL RMPP WVNI WLLG SICL SMSL HFLI LYVD PLPM IFKL RALD LTQW LMVL KISL PVIG LDEI LKFV ARNY LEDP EDER RK
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:ATP2A; SERCA1; SERCA1/ATP2A1
Positive Sample:Mouse skeletal muscle
Conjugate:Unconjugated
Cellular Localization:Endoplasmic reticulum membrane, Sarcoplasmic reticulum membrane
Calculated MW:95kDa/110kDa
Observed MW:110kDa

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.

Purification Method:Affinity purification
Gene ID:487
Clone Number:ARC2207
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse skeletal muscle, using SERCA1/ATP2A1 Rabbit mAb (CAB19639) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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