The SATB2 Monoclonal Antibody (CAB19837) is a valuable tool for researchers studying SATB2, a transcription factor involved in chromatin remodeling and gene regulation. This antibody, produced using hybridoma technology, exhibits high specificity and sensitivity for SATB2 in human samples, making it suitable for various applications including immunohistochemistry and flow cytometry.SATB2 is known to play a key role in cell differentiation and development, particularly in the skeletal and nervous systems. Aberrant expression of SATB2 has been linked to various diseases, making it a potential therapeutic target for conditions like osteoporosis and neurological disorders.
By targeting SATB2 with this antibody, researchers can gain insights into its function and explore its potential as a diagnostic or therapeutic biomarker in disease settings.Overall, the SATB2 Monoclonal Antibody (CAB19837) offers researchers a reliable tool for investigating the role of SATB2 in health and disease, paving the way for advancements in personalized medicine and targeted therapies.
Product Name:
SATB2 Rabbit Monoclonal Antibody
SKU:
CAB19837
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SATB2 (Q9UPW6).
WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
GLSS; DEL2Q32Q33; C2DELq32q33; SATB2
Positive Sample:
Rat brain
Conjugate:
Unconjugated
Calculated MW:
83kDa
Observed MW:
100kDa
This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein.
Purification Method:
Affinity purification
Gene ID:
23314
Clone Number:
ARC2363
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat brain, using SATB2 Rabbit mAb (CAB19837) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
