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SARS-CoV Spike S1 Rabbit Polyclonal Antibody (CAB20604)

SKU:
CAB20604
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Virus
Host Species:
Rabbit
Isotype:
IgG
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SARS-CoV Spike S1 Rabbit Polyclonal Antibody
SKU:CAB20604
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:SARS-CoV
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of coronavirus Spike S1 (NP_828851.1).
Sequence:MFIF LLFL TLTS GSDL DRCT TFDD VQAP NYTQ HTSS MRGV YYPD EIFR SDTL YLTQ DLFL PFYS NVTG FHTI NHTF GNPV IPFK DGIY FAAT EKSN VVRG
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:E2; SARS-CoV-2 Spike S1
Positive Sample:293T
Conjugate:Unconjugated
Calculated MW:139kDa
Observed MW:200kDa

The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.

Purification Method:Affinity purification
Gene ID:1489668
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SARS-CoV-2 Spike S1 Rabbit pAb (CAB20604) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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