The Anti-SARS CoV Spike S1 Antibody (CAB20604) is a crucial tool for researchers studying the S1 spike protein of the SARS-CoV virus, which is responsible for the initial attachment and entry of the virus into host cells. This antibody, produced in rabbits, is highly specific to the SARS-CoV spike S1 protein and has been validated for use in a variety of applications, including Western blotting and immunofluorescence.
With the ongoing threat of coronaviruses like SARS-CoV, understanding the structure and function of viral proteins such as the spike S1 protein is essential for developing diagnostic tools, vaccines, and antiviral drugs. The Anti-SARS CoV Spike S1 Antibody provides researchers with a reliable tool for detecting and studying this critical component of the virus, driving advancements in the fight against coronaviruses.
Product Name:
SARS-CoV Spike S1 Rabbit Polyclonal Antibody
SKU:
CAB20604
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
SARS-CoV
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of coronavirus Spike S1 (NP_828851.1).
The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.
Purification Method:
Affinity purification
Gene ID:
1489668
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using SARS-CoV-2 Spike S1 Rabbit pAb (CAB20604) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
