SARS-CoV Spike RBD Rabbit Polyclonal Antibody (CAB20606)
- SKU:
- CAB20606
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
Product Name: | SARS-CoV Spike RBD Rabbit Polyclonal Antibody |
SKU: | CAB20606 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | SARS-CoV |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of coronavirus Spike RBD (NP_828851.1). |
Sequence: | ADYS VLYN STFF STFK CYGV SATK LNDL CFSN VYAD SFVV KGDD VRQI APGQ TGVI ADYN YKLP DDFM GCVL AWNT RNID ATST GNYN YKYR YLRH GKLR P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | E2; SARS-CoV Spike RBD |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Calculated MW: | 139kDa |
Observed MW: | 200kDa |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It's been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.
Purification Method: | Affinity purification |
Gene ID: | 1489668 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |