SARS-CoV Spike Rabbit Polyclonal Antibody (CAB20605)
- SKU:
- CAB20605
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
Product Name: | SARS-CoV Spike Rabbit Polyclonal Antibody |
SKU: | CAB20605 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | SARS-CoV |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of coronavirus Spike (NP_828851.1). |
Sequence: | DVNC TDVS TAIH ADQL TPAW RIYS TGNN VFQT QAGC LIGA EHVD TSYE CDIP IGAG ICAS YHTV SLLR STSQ KSIV AYTM SLGA DSSI AYSN NTIA IPTN F |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | E2; SARS-CoV Spike |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Calculated MW: | 139kDa |
Observed MW: | 200kDa |
The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.
Purification Method: | Affinity purification |
Gene ID: | 1489668 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |