SARS-CoV-2 Spike Rabbit Polyclonal Antibody (CAB20137)
- SKU:
- CAB20137
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
Product Name: | SARS-CoV-2 Spike Rabbit Polyclonal Antibody |
SKU: | CAB20137 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | SARS-CoV-2 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of coronavirus Spike (YP_009724390.1). |
Sequence: | PGTN TSNQ VAVL YQDV NCTE VPVA IHAD QLTP TWRV YSTG SNVF QTRA GCLI GAEH VNNS YECD IPIG AGIC ASYQ TQTN SPRR ARSV ASQS IIAY TMSL G |
Tested Applications: | WB IF/ICC IP ELISA DB |
Recommended Dilution: | DB,1:500 - 1:2000 WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | spike glycoprotein; SARS-CoV-2 Spike |
Positive Sample: | 293T |
Calculated MW: | 141kDa |
Observed MW: | 110kDa/180kDa |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests.
Purification Method: | Affinity purification |
Gene ID: | 43740568 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |