The Anti-SARS-CoV-2 ORF6 Antibody (CAB20324) is a vital tool for research involving the ORF6 protein of the SARS-CoV-2 virus. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting. By specifically binding to the ORF6 protein, this antibody enables precise detection and analysis in different cell types, making it an essential resource for studies in virology and infectious disease research.
The ORF6 protein of SARS-CoV-2 is known to play a crucial role in viral replication and evasion of host immune responses. Understanding the function and interactions of ORF6 is key to developing effective treatments and vaccines for COVID-19. By targeting ORF6 with this antibody, researchers can gain valuable insights into the mechanisms of viral infection and host immune evasion strategies employed by SARS-CoV-2.
Product Name:
SARS-CoV-2 ORF6 Rabbit Polyclonal Antibody
SKU:
CAB20324
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
SARS-CoV-2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-61 of coronavirus ORF6 (YP_009724394.1).
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF6 encodes a viral accessory protein. Based on its similarity to other coronavirus proteins, ORF6 protein is thought to play a role in viral pathogenesis.
Purification Method:
Affinity purification
Gene ID:
43740572
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of 293T cells, using SARS-CoV-2 ORF6 antibody (CAB20324) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.